---
title: "Is a Genetic Mutation a Disability? The Sixth Circuit Says Maybe."
description: ""
url: "https://wimlaw.com/articles/genetic-mutation-disability"
date: "2026-06-22T11:37:27+00:00"
language: "en-US"
---

#  Is a Genetic Mutation a Disability? The Sixth Circuit Says Maybe.

Written on July 02, 2020.

*Tag(s):* [Kathleen J. Jennings](https://wimlaw.com/index.php?option=com_tags&view=tag&id%5B0%5D=8:kathleen-j-jennings)

Is a genetic mutation disability? Specifically, is the genetic mutation known as a BRCA1 mutation (Angelina Jolie revealed that she has this mutation) a “disability” under the Americans with Disabilities Act (ADA) even though the employee has not yet developed breast cancer? In a case of first impression, the Sixth Circuit Court of Appeals said **maybe**. (*Darby v. Childvine, Inc.*, No. 19-4214 (6th Cir. June 30, 2020)).

Sherryl Darby underwent a double mastectomy following diagnosis of the growth of abnormal pre-cancerous cells along with the BRAC1 genetic mutation that contributes to abnormal cell growth. Invoking the Americans with Disabilities Act and Ohio law, Darby alleged she was discriminated against when her employer terminated her employment upon learning of her condition. (Interestingly, she did not bring a claim under GINA.) The district court dismissed her claims, concluding that Darby’s genetic mutation had not yet manifested into a disability cognizable under the ADA. The Sixth Circuit reversed the decision below and held that Ms. Darby’s allegations were sufficient to survive a motion to dismiss.

The key issue was whether Darby’s genetic mutation, which had not manifested in cancer, constitutes a “disability” under the ADA. Under the ADA, a disability as defined as “a physical or mental impairment that substantially limits one or more \[of her\] major life activities.” 42 U.S.C. § 12102(1)(A).

Darby argued that her impairment substantially limits her normal cell growth as compared to the general population due to both a genetic mutation (BRCA1) that limits her normal cell growth and a medical diagnosis of abnormal epithelial cell growth serious enough to warrant a double mastectomy. For purposes of Rule 12(b)(6) motion to dismiss, the Court agreed and found that Darby’s gene mutation and abnormal cell growth, though not cancerous, qualify as a disability under the ADA. See *Lonergan v. Fla. Dep’t of Corr.*, 623 F. App’x 990 , 993 (11th Cir. 2015) (finding plaintiff successfully alleged a substantial limitation in major life activity of normal cell growth in part due to allegation of “abnormal growth of pre-cancerous cells”).

The Court further noted that Darby’s claims are entitled to further consideration through discovery: “Particularly with less-well-understood medical issues like the BRCA1 genetic mutation and its effects on “abnormal epithelial cells,” expert medical testimony may help reveal whether Darby’s condition “substantially limits” normal cell growth.”

The Court also stated that a genetic mutation that merely predisposes an individual to other conditions, such as cancer, is not itself a disability under the ADA. The terms of the Act do not reach that far. See *Shell v. Burlington N. Santa Fe Ry. Co*., 941 F.3d 331 , 335-36 (7th Cir. 2019) (finding no ADA disability where plaintiff based his claim on conditions he feared he would develop as a result of obesity). In other words, in order to rise to the level of a disability, a genetic mutation must have some immediate effect on a person’s body that substantially limit a major life activity.

**The takeaway:** This is an area of the law that is still developing. Thus, each situation must be considered by an employer on a case by case basis. In order to avoid potential liability under the ADA, an employer must be extremely cautious in its treatment of any employee who presents medical issues related to a genetic predisposition or mutation.

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 ![Kathleen J. Jennings](https://wimlaw.com/images/resources/articles/2020/06/kathleen-portrait-300.jpg)

 Kathleen J. Jennings

Former Principal

Kathleen J. Jennings is a former principal in the Atlanta office of Wimberly, Lawson, Steckel, Schneider, & Stine, P.C. She defends employers in employment matters, such as sexual harassment, discrimination, Wage and Hour, OSHA, restrictive covenants, and other employment litigation and provides training and counseling to employers in employment matters.

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